- | Effects Determination for Malathion and the Delta Smelt and California Tiger Salamander Additional ES Files (California Red-legged Frog and other California Listed Species) | - | - | - |
- | Effects Determination for Malathion and the California Red-legged Frog Additional ES Files (California Red-legged Frog and other California Listed Species) | - | - | - |
- | Effects Determinations for Malathion Additional ES Files | - | - | - |
- | DER #4. Malathion: 1-Year Chronic Oral Toxicity Study in Dogs. Tegeris Laboratories. 1987. MRID 40188501. HED Doc. No. 006349. (PDF, 17 pp, 931K) | Toxicology Branch | - | 40188501 |
- | DER #17; Malathion: Metabolism Study in Sprague-Dawley Rats. Midwest Research Institute. 1989. MRID No. 41367701. HED Doc No. 007791. Registration Data removed from pages 10-18. (PDF, 18 pp, 489K) | Toxicology Branch | - | 41367701 |
- | DER #12; Malathion: 21-Day Dermal Toxicity Study in Rabbits. MB Research Laboratories. 1988. MRID No. 41054201. HED Doc Nos. 008714 & 009385. (PDF, 22 pp, 1MB) | Toxicology Branch | - | 41054201 |
- | DER #8; Malathion: Acute Delayed Neurotoxicity Study in Hens. Bio-Life Associates. 1988. MRID No. 40939301. HED Doc Nos. 007524, 008026. (PDF, 22 pp, 1MB) | Toxicology Branch | - | 40939301 |
- | DER #13; Malathion: 13-Week Subchronic Inhalation Toxicity Study in Sprague-Dawley Rats. Bio-Research Laboratories (Canada). 1994. MRID No. 43266601. HED Doc No. 011516. (PDF, 26 pp, 2MB) | Toxicology Branch | - | 43266601 |
- | DER #7a. Malathion: Range-Finding Developmental Toxicity Study in Rabbits. Food & Drug Research Laboratories. 1985. MRID No. 00152569. HED Doc. No. 007376. Registration Data removed from pages 6-26. (PDF, 26 pp, 173K) | Toxicology Branch | - | 152569 |
- | DER #5. Malathion: 2-Generation Reproduction Study in Sprague-Dawley Rats. Bio/dynamics. 1990. MRID 41583401. HED Doc. No. 009365. (PDF, 28 pp, 1MB) | Toxicology Branch | - | 41583401 |
- | DER #6. Malathion: Developmental Toxicity Study in Sprague-Dawley Rats. Argus Research Laboratory. 1989. . MRID No. 41160901. HED Doc. No. 008384. Registration Data removed from pages 13-28. (PDF, 28 pp, 674K) | Toxicology Branch | - | 41160901 |
- | DER #7. Malathion: Developmental Toxicity Study in Rabbits. Food & Drug Research Laboratories 1985. MRID No. 00152569, 40812001. HED Doc. No. 007376. (PDF, 7 pp, 354K) | Toxicology Branch | - | 152569... [More] |
- | DER #2. Malathion: 18-Month Carcinogenicity Study in B6C3F1 Mice. International Research & Developmental Corp. 1994. MRID No. 43407201. HED Doc. No. 011455. Registration Data removed from pages 45-48 & 66-78. (PDF, 78 pp, 4MB) | Toxicology Branch | - | 43407201 |
- | Recommended International Tolerances for Pesticide Residues (PDF, 4 pp, 247K) | J. G. Cummings | Petitions Evaluation Branch, FDA | - |
- | Review of a 6(a)(2) and Follow-Up Data Submitted for Developmental Neurotoxicity and Acetylcholinesterase Studies in Rats [re malathion; see 12/14/2000 & 4/19/2001]. (PDF, 2 pp, 73K) | Carmelita White | SRRD | - |
- | DER #13a; Malathion: 2-Week (Range-finding) Inhalation Study in Sprague-Dawley Rats. MRID No. 44554301; 82-4. (PDF, 14 pp, 685K) | Brian Dementi | Toxicology Branch | 44554301 |
- | Special Study, Effects on Cholinesterase in Adult & Juvenile CD Rats, Companion Study to Development Neurotoxicity Study 870.6300. Tox Review No. 0050550. MRID No. 45566201. (PDF, 22 pp, 2MB) | Brian Dementi | Toxicology Branch | 45566201 |
08/21/2007 | Malathion and Malaoxon: Follow-up Analysis of Acute Dose Comparative Cholinesterase Study Protocol PC Code: 057701. Barcode: DP# 342339. TXR No. 0054671 (PDF, 6 pp, 187K) | Deborah Smegal | Re-Registration Branch 2 | - |
06/28/2007 | Malathion and Malaoxon: Review of Acute Dose Comparative Cholinesterase Study Protocol PC Code: 057701. Barcode: DP# 340518. TXR No. 0054632 (PDF, 9 pp, 275K) | Deborah Smegal | Re-Registration Branch 2 | - |
03/30/2007 | Data Evaluation Record (DER) for Special Study: Repeat Dose Comparative Cholinesterase Study of Malathion and Malaoxon in Juvenile Rats. DP Barcode: D332783. TXR # 0054537. (MRID Nos. 46822201, 46821703) (PDF, 19 pp, 695K) | Gerome Burke | Toxicology Branch | 46821703... [More] |
04/11/2005 | Benchmark dose analysis of brain and RBC data from the malathion comparative cholinesterase study in juvenile and adult rats (MRID No. 45566201). TXR No. 0053251 (PDF, 59 pp, 152K) | Anna Lowit | Reregistration Branch 2 | 45566201 |
11/19/2004 | Malathion use as a mosquitocide and potential risk to listed salmonids. DP Barcode: 308617 (PDF, 9 pp, 661K) | Norman Birchfield | Environmental Risk Branch I | - |
11/09/2004 | D292658: Malathion (057701) Amendment 1 to comparative cholinesterase inhibition study in adult and juvenile rats (MRlD 46005001). TXR No. 0052129 (PDF, 13 pp, 547K) | Brian Dementi | Toxicology Branch | - |
04/02/2003 | Efficacy Review - Ortho Malathion 50 Insect Spray (PDF, 4 pp, 612K) | Joanne Edwards | Insecticide-Rodenticide Branch RD | 45829601... [More] |
11/08/2002 | Malathion: Updated Revised Occupational Exposure and Risk Assessment for the Interim Reregistration Eligibility Decision (IRED) Document. (DP Barcode: D286796; EPA MRID Nos.: 45005910, 45491901, 45138202, 45491902, 45138201, 45469501) (PDF, 440 pp, 20MB) | Jack Arthur | Registration Action Branch 3 | 45005910... [More] |
08/22/2002 | D282204. Malathion (057701) Developmental neurotoxicity data reviews: 1) developmental neurotoxicity study in rats 2) comparative cholinesterase inhibition study in adult and juvenile rats 3) dose range-finding developmental neurotoxicity in rats. (PDF, 100 pp, 8MB) Attachments | Susan Makris | Toxicology Branch | - |
04/22/2002 | DER #7b. Malathion: Registrant Comments on Agency review of prenatal developmental Toxicity study in rabbits (MRID No. 45626801) Supplemental to MRID Nos. 00152569 & 40812001. Tox Review No. 0050549. (PDF, 9 pp, 672K) | Susan Makris | Toxicology Branch | 152569... [More] |
04/19/2001 | Review of a February 13, 2001 FIFRA 6(a)(2) Submission of Preliminary Data from a Developmental Neurotoxicity Study on Malathion Performed in CD Rats. Tox review 014544. (PDF, 14 pp, 1MB) | Brian Dementi | Toxicology Branch | - |
12/14/2000 | Review of FIFRA 6(a)(2) Data Submission for a Dose Range- Finding Study in Sprague-Dawley Rats Intended to Provide Guidance for Dose Selection for the Definitive Developmental Neurotoxicity and Acetylcholinesterase Studies... Tox review 014413 (PDF, 9 pp, 788K) | Brian Dementi | Toxicology Branch | - |
09/12/2000 | DER #4a. Malathion: 28-day oral toxicity study in beagle dogs. (MRID 45077703); Review of 28-Day Oral Toxicity Study of Malathion in Beagle Dogs (MRID No. 45077703); Recommendations for Further Testing in Dogs. Tox Review No. 014336. (PDF, 8 pp, 590K) | Brian Dementi | Toxicology Branch | 45077703 |
02/10/2000 | Malathion - Report of the Cancer Assessment Review Committee Attached: 2/2/2000 Final Cancer Assessment Document; Evaluation of the Carcinogenic Potential of Malathion. MRID No. 43975201. Tox review 013991. (PDF, 54 pp, 4MB) | Brian Dementi | Toxicology Branch | 43975201 |
01/18/2000 | DER #14b; Malathion: Published Study; Ehrich, M., Shell,L., Rozum, M., and Jortner, B.S. (1993) Short-term clinical & neuropathologic effects of cholinesterase inhibitors in rats. J. Am Coll. Toxicol. 12(1), 55-68 (MRID No. 45045001) TXR0050532. (PDF, 16 pp, 1MB) | Toxicology Branch | - | 45045001 |
11/18/1999 | Malathion: Study Pathologist's Responses (MRIDs 44837001, 44970601, 44970501) to Health Effects Division's Questions on the Nasal Tissue Histopathology Re-evaluation (MRID 44782301) of the Combined Chronic Toxicity/Carcinogenicity Study in the F344 Rat� (PDF, 14 pp, 883K) | Brian Dementi | Toxicology Branch | 44782301... [More] |
11/08/1999 | Malathion: Preliminary Risk Assessment for the Reregistration Eligibility Decision (RED) Document. Chemical No. 057701. Case No. 0248. Barcode D255364. Tox review 013873 (PDF, 72 pp, 5MB) | Paula Deschamp | Reregistration Branch 2, HED | - |
11/03/1999 | MALATHION: Preliminary Dietary Risk Assessment (Revised) (PDF, 15 pp, 912K) | Richard Griffin | Reregistration Branch II, HED | - |
10/06/1999 | MALATHION: Preliminary Dietary Risk Assessment (PDF, 15 pp, 1MB) | Richard Griffin | Reregistration Branch II, HED | - |
05/27/1999 | Review of the Histopathology Re-Assessment of Nasal Tissues for the Malathion 24-Month Oral (Dietary) Combined Toxicity/ Carcinogenicity Study in the F344 Rat (MRID 44782301). Pages 26-81 removed, registrant data. Tox review 013719. (PDF, 81 pp, 2MB) | Brian Dementi | Toxicology Branch | 44782301 |
05/05/1999 | Review of Histopathology Assessment of Nasal Tissues for the Malathion 18-Month Oral (Dietary) Carcinogenicity Study in Mice (MRID: 44733501; 44792301). Pages 14-25 removed, registrant data. Tox review 013722. (PDF, 25 pp, 1MB) | Brian Dementi | Toxicology Branch | 44733501... [More] |
02/12/1999 | Cancer Assessment Review Committee Meeting on Malathion. Pages 187-190, 208-219 removed, registrant data. (page 2: 2/12/99; William Burnam; Additional Malathion Information for... Cancer Peer Review; page 3: 9/8/97; Jess Rowland; Cancer Assessment� (PDF, 276 pp, 19MB) | Sanjivani Diwan | Health Effects Division | - |
02/11/1999 | Supplemental Information for the Cancer Assessment Review Committee Meeting Scheduled for February 24, 1999 to Resume Evaluation of the Malathion Carcinogenicity Database. Pages 13-84, 143-149 removed, registrant data. (PDF, 154 pp, 5MB) Attachments | Brian Dementi | Toxicology Branch | - |
01/08/1999 | Malathion: PC Code 057701. Case 0248. Magnitude of Residues in/on avocados, beans (dry), blueberries, grapes, grasses, onions (dry bulb), onions (green), rice, spring wheat, winter wheat (OPPTS 860.1500) & an orange processing study (OPPTS 860.1520). (PDF, 55 pp, 3MB) Attachments | Manying Xue | Chemistry & Exposure Branch I | - |
12/22/1998 | MALATHION: - RE-EVALUATION A Report of the Hazard Identification Assessment Review Committee. (PDF, 152 pp, 6MB) | Jess Rowland | Hazard Identification Assessment Review Committee | - |
12/01/1998 | Review of Pathology Working Group Report (PWG) Peer Review of Proliferative Lesions of the Liver in Male B6C3F1 Mice in an 18-Month Oral (Dietary) Oncogenicity Study in Micce of Malthion. MRID 44554901. Tox Review 013721. (PDF, 23 pp, 2MB) | Brian Dementi | Toxicology Branch | 44554901 |
11/05/1998 | Malathion: PC Code 057701. Registration Case 0248. Magnitude of Residues in Alfalfa, Clover & Cottonseed (OPPTS 860.1500) Processing Studies in Grapes, Cottonseed, Rice & Field Corn (OPPTS 860.1520). MRID Nos. 43546101, 43545201, 43596601, 43577401, 4358 (PDF, 43 pp, 3MB) | Manying Xue | Chemistry & Exposure Branch I | 43546101... [More] |
09/22/1998 | EFED RED Chapter for Malathion PC Code 057701; Case No. 818961 DP Barcodes: D238903 and D238906 and D238904 (PDF, 158 pp, 11MB) | Brian Montague | Environmental Risk Branch | - |
08/18/1998 | Review of Malathion Incident Reports. (PDF, 39 pp, 3MB) | Jerome Blondell | Chemistry & Exposure Branch | - |
07/13/1998 | Malathion: PC Code 057701. Case 0248. Magnitude of Residue of Malathion & malaoxon in/on Winter Wheat Grain & its Processed Commodities. MRID No. 43510501. (PDF, 8 pp, 492K) | Manying Xue | Chemistry & Exposure Branch I | 43510501 |
05/26/1998 | Malathion: PC Code 057701. Case 0248. Magnitude of Residues of Malathion & Malaoxon in/on Stored Grains &Processed Commodities. (OPPTS 860.1520). MRID Nos. 436661401 & 43666801. (PDF, 18 pp, 1MB) | Manying Xue | Chemistry & Exposure Branch I | 43661401... [More] |
02/18/1998 | DRES Analysis for Malathion '... Please perform a chronic and acute DRES analysis for malathion using additional PDP information provided...' (PDF, 2 pp, 78K) | Martha Lamont | Registration Action Branch I | - |
12/17/1997 | Malathion - Report of the Hazard Identification Assessment Review Committee Tox review 012440. (PDF, 53 pp, 3MB) | Jess Rowland | Science Analysis Branch HED | - |