- | EPA Reg. #100-EUP-AT, 9H5231, 9G2234 (Curacron 6E Insecticide - Soybeans), 100-LOI, 8F2057, 8H5177 (Curacon - Growing Cotton... Impurity, inert ingredient, and commercial financial information on pages 1, 4 and 5 is not included. Tox review 000821 (PDF, 62 pp, 9MB) | William Woodrow | Toxicology Branch | - |
10/19/2016 | Amendment to: Profenofos: Human Health Draft Risk Assessment (ORA)
for Registration Review (PDF, 39 pp, 2MB) | Sarah Levy | HED | - |
01/31/2007 | Response to Profenofos freshwater fish full life cycle data waiver request. DP Barcode: D280410 (PDF, 1 pp, 30K) | Christopher Salice | Environmental Risk Branch IV | - |
09/20/2005 | PROFENOFOS: Data Evaluation Record of a Developmental Neurotoxicity Toxicity Study. CAS # 41198-08-7
DP Barcode D293052. MRID No. 46025401 & 46025402. TXR No. 0052102 (PDF, 30 pp, 1MB) | Ayaad Assaad | Toxicology Branch | 46025401... [More] |
11/17/2004 | Secondary Review of the Developmental Neurotoxicity Studies. (MRIDs 46025401 and 46025402). DP BARCODE: D293052. TXR#: 0052102 (PDF, 45 pp, 2MB) | Jess Rowland | Science Information Management Branch | 46025401... [More] |
06/26/2002 | Profenofos: Review of Acute and Repeated Exposure Comparative Cholinesterase Study Protocols. DP Barcode: D281191. TXR #: 0050512 (PDF, 4 pp, 129K) | William Sette | Toxicology Branch | - |
06/16/1999 | Human Health Risk Assessment, Profenofos (PDF, 58 pp, 4MB) | Richard Griffin | Health Effects Division | - |
06/16/1999 | Reregistration Eligibility Decision Environmental Risk Assessment for Profenofos (PDF, 49 pp, 3MB) | Denise Keehner | Environmental Fate & Effects Division | - |
06/15/1999 | Resonse to Public Comments on Preliminary Risk Assessments for the Organophosphate Profenofos (PDF, 22 pp, 2MB) | Carmelita White | SRRD | - |
04/22/1999 | EFED Response to USDA/Land Grant University Comments on the Profenofos Updated Risk Assessment; Comments Dated April 1, 1999 (PDF, 2 pp, 85K) | Nelson Thurman | Environmental Risk Branch IV | - |
12/01/1998 | EFED Response to Comments from the Registrant and the Public Regarding the Draft Profenofos RED (PDF, 9 pp, 433K) | Ann Stavola | Ecological Effects Branch | - |
08/12/1998 | To: Robert E.M. Wurz Novartis Crop Protection, Inc. Profenofos Fish Kills in Southern United States (PDF, 7 pp, 417K) | Jack Housenger | SRRD | - |
05/14/1998 | Summary of EFED Concerns Regarding Fish Kill Incidents Attributed to Use of Profenofos on Cotton (PDF, 5 pp, 346K) | Richard Lee | Environmental Risk Branch 4 | - |
02/06/1998 | To: Robert E.M. Wurz Novartis Crop Protection, Inc. Profenofos Reregistration; HED Chapter with FQPA Update; HED's Response to Rebuttal on Toxicology Section (PDF, 6 pp, 392K) Attachments | Kylie Rothwell | SRRD | - |
01/21/1998 | Profenofos (PC Code 111401). FQPA Update of the HED Chapter of the Reregistration Eligibility Decision Document. Case No. 2540. (PDF, 58 pp, 4MB) | Richard Griffin | Health Effects Division | - |
09/25/1997 | Profenofos - FQPA Requirement - Report of the Hazard Identification Assessment Review Committee. Tox review 012326. (PDF, 5 pp, 294K) | Jess Rowland | Science Analysis Branch HED | - |
09/25/1996 | Product Name: Curacron. Common Name: Profenofos. Type of Product: Acaracide, insecticide. Company Name: Ciba-Geigy. DP Barcode: D222822, D222825. To provide aquatic exposure assessment for Profenofos
through PRZM-EXAMS Computer modelling (PDF, 20 pp, 950K) | Ronald Parker | Environmental Fate & Ground Water Branch | - |
08/30/1996 | EFED Risk Characterization and Recommendations for the Reregistration of Profenofos (PDF, 9 pp, 616K) | David Farrar | Environmental Fate & Effects Branch | - |
06/18/1996 | The HED Chapter of the Reregistration Eligibility Decision Document (RED) for Profenofos (PDF, 49 pp, 3MB) | Kathleen Martin | Risk Characterization & Analysis Branch | - |
06/17/1996 | EFED Text Proposed for the Profenofos RED (List B; Case 2540; PC Code 111401) (PDF, 25 pp, 2MB) | David Farrar | Environmental Fate & Effects Branch | - |
05/09/1996 | Dietary Exposure Aanalysis for Profenofos in Support of the Reregistration Eligibility Decision (PDF, 11 pp, 716K) | Brian Steinwand | Science Analysis Branch | - |
02/06/1996 | RfD/Peer Review Report of Profenofos (Curacron)... (PDF, 11 pp, 730K) | George Ghali | Health Effects Division | - |
03/14/1995 | Profenofos. Nature of the Residue in Cotton. Case No. 2540. Chemical No. 111401. MRID No. 43186801. DP Barcode: D201827. CBRS No. 13539. Radiovalidation data. MRID No. 43203501. DP Barcode: D203218. CBRS No. 13725. (PDF, 11 pp, 693K) | Catherine Eiden | Chemistry Branch II | 43186801 |
11/06/1992 | Profenofos. Chetram, R.S. 1990. Tier 2 Vegetative Vigor Nontarget Phytotoxicity Study Using Profenofos Technical (Curacron). MRID No. 461273-05 (PDF, 10 pp, 502K) | Richard Felthousen | Ecological Effects Branch | 46127305 |
09/02/1992 | Curacron. Review Registrant Rebuttal to EEB Review of Avian Dietary Studies. Profenofos (PDF, 6 pp, 323K) | Richard Felthousen | Ecological Effects Branch | - |
06/19/1991 | Profenofos. Chetram, R.S. 1990. Tier 2 Seedling Emergence Nontarget Phytotoxicity Study Using Profenofos Technical (Curacron). MRID No. 416273-07 (PDF, 11 pp, 533K) | Mark Mossler | KBN Engineering & Applied Sciences Inc. | 41627307 |
06/19/1991 | Profenofos. Chetram, R.S. 1990. Tier 2 Seed Germination Nontarget Phytotoxicity Study Using Profenofos Technical (Curacron). MRID No. 416273-06 (PDF, 6 pp, 306K) | Mark Mossler | KBN Engineering & Applied Sciences Inc. | 41627306 |
06/19/1991 | Profenofos. Winter, P.A. 1990. Profenofos: An Acute Contact Study with the Honey Bee. MRID No. 416273-08 (PDF, 8 pp, 2MB) | Mark Mossler | KBN Engineering & Applied Sciences Inc. | 41627308 |
06/19/1991 | Profenofos. Bellantoni, D.C. 1990. Profenofos Technical: A 48-Hour Static Acute Toxicity Text with the Cladoceran (Daphnia magna). MRID No. 416273-04 (PDF, 8 pp, 397K) | Louis Rifici | KBN Engineering & Applied Sciences Inc. | 41627304 |
06/18/1991 | Study Type: Avian Single dose Oral LD50 Test. Species Tested: Mallard duck. MRID No. 416273-01 (PDF, 10 pp, 480K) | Richard Felthousen | Ecological Effects Branch | 41627301 |
06/18/1991 | Study Type: Avian Dietary LC50 Test. Species Tested: Mallard duck. MRID No. 416273-02 (PDF, 12 pp, 613K) | Richard Felthousen | Ecological Effects Branch | 41627302 |
06/18/1991 | Study Type: Avian Dietary LC50 Test. Species Tested: Bobwhite quail. MRID No. 416273-03 (PDF, 12 pp, 597K) | Marise Robbins | KBN Engineering for EEB | 41627303 |
02/03/1987 | Reference Doses (RFDs) for Oral Exposure Chemical: Curacron/Profenofos Ciba-Geigy Limited 1981 6-Month Dog Feeding Study (PDF, 3 pp, 147K) | George Ghali | Health Effects Division | - |
12/05/1986 | Reg./File # 100-599. Amend to Add Application on Soybeans. Profenofos Is Currently Registered for Cotton (PDF, 6 pp, 246K) | Emil Regelman | Exposure Assessment Branch | - |
11/17/1985 | Response to Comments on Review of Curacron Rabbit Teratology Study. Acc. No. 254648. Caswell #266AA. Tox review 004780 (PDF, 2 pp, 178K) | Gary Burin | Toxicology Branch | - |
04/10/1985 | Reg./File No.: 100-599. 1984 Pond Monitor Survey Study to Satisfy for Full Registration Requirement (PDF, 11 pp, 469K) | Carolyn Offutt | Exposure Assessment Branch | - |
05/23/1984 | Reg. No.: 100-599. Runoff. study review to satisfy a conditional registration requirement (PDF, 17 pp, 645K) | Carolyn Offutt | Exposure Assessment Branch | - |
10/21/1983 | Review of Curacron Rabbit Teratology Study, Accession Number 250451. Tox review 003323 (PDF, 3 pp, 369K) | Gary Burin | Toxicology Branch | - |
12/13/1982 | Re-Evaluation of Validated IBT Study of Curacron; Acute Delayed Neurotoxicity in Chickens, Study #8580-10426. Tox review 002929 (PDF, 2 pp, 146K) | Orville Paynter | Toxicology Branch | - |
12/10/1982 | Re-Evaluation of Validated IBT Study of Curacron; Acute Delayed Neurotoxicity in Chickens, Study #8580-10426. Inert ingredient information on pages 2 and 3 not included. Tox review 002331 (PDF, 4 pp, 283K) | Gary Burin | Toxicology Branch | - |
10/26/1982 | Review of Curacron Teratology Studies; 100-598, 599; PP#8F2057, 8H5177. Caswell #266AA, Acc. Nos. 247784-7, 247919, 070884. Tox review 002247 (PDF, 7 pp, 869K) | Gary Burin | Toxicology Branch | - |
10/21/1982 | Comments on Curacron Neurotoxicity Including the Evaluation of a Validated Acute Neurotoxicity Study in Chickens, IBT #8580-111870 Tox review 002236 (PDF, 3 pp, 188K) | Gary Burin | Toxicology Branch | - |
10/19/1982 | Review of Acute Toxicology Studies for Curacron, Accession No. 247933 Tox review 002238 (PDF, 5 pp, 509K) | Gary Burin | Toxicology Branch | - |
05/28/1982 | Addendum to Validation and Review of Additional Histopathology Data for IBT Three-Generation Reproduction Study of Curacron in Albino Rats; IBT No. 623-07924, Accession No. 247456 Tox review 003001 (PDF, 2 pp, 239K) | Gary Burin | Toxicology Branch | - |
04/22/1982 | EPA Reg. No. 100-599, 100-598, PP#8F2057, 9H5231, and FAP 8H5177 - Profenofos (Curacron) on Growing Cotton. Manufacturing process information on page 2 is not included. Tox review 002535 (PDF, 7 pp, 703K) | William Woodrow | Toxicology Branch | - |
04/19/1982 | EPA Reg. #100-599, 100-598, PP#8F2057, 9H5231, and FAP 8H5177 - Profenofos (Curacron) on Growing Cotton. Caswell #266AA, Acc. Nos. 070513, 245718, 245717... Impurity and inert ingredient information on pages 2 and 5 not included. Tox review 001783 (PDF, 41 pp, 6MB) Attachments | William Woodrow | Toxicology Branch | - |
03/25/1982 | Review of Validated IBT Rat Reproduction Study of Curacron (CGA-15324), IBT No. 623-07924, Tox. Chem. 266A Tox review 001573 (PDF, 4 pp, 418K) | Gary Burin | Toxicology Branch | - |
03/22/1982 | IBT Validation Report, IBT No. 623-07924, Three-Generation Reproduction Study with CGA-15324 Technical in Albino Rats Tox review 001629 (PDF, 1 pp, 61K) | Gary Burin | Toxicology Branch | - |
03/15/1982 | Reg. No.: 100-LOO Reevaluation of drift and runoff data Pages 4-22 removed, registrant data. (PDF, 22 pp, 149K) | Willa Garner | Environmental Fate Branch | - |
01/29/1982 | EXAMS Model Determinations for Aquatic Systems Adjacent to Cotton (PDF, 4 pp, 177K) | Willa Garner | Environmental Fate Branch | - |