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EPA has produced a vast collection of science-related documents to support pesticide registration decisions. Below you will find a subset of documents that, generally, have been requested by the public through the Freedom of Information Act (FOIA) process. Each of these documents has been reviewed to ensure that any proprietary information is not included.

If you wish to obtain a document that is not currently posted, you may do so by filing a FOIA request.

   
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  • 1 - 50 of 67
DateTitleAuthorOrganizationMRID
12/08/2005Formation of Bromate Ion from Application of Dihalodialkylhydantoin Sanitizers (BCDMH and DBDMH) into Swimming Pools and Associated Cancer Risks for Swimmers. DP Barcode 324327. (PDF, 14 pp, 739K)Tim LeightonAntimicrobials Division-
08/28/20005,5-Dimethylhydantoin - Revised Report of the Hazard Identification Assessment Review Committee. Tox review 014298. (PDF, 18 pp, 1MB)Timothy McMahonRisk Assessment & Science Support Branch-
08/14/20005,5-Dimethylhydantoin - Report of the Hazard Identification Assessment Review Committee. Tox review 014292. (PDF, 18 pp, 1MB)Timothy McMahonRisk Assessment & Science Support Branch-
07/14/1999Efficacy Review and Label Review for "Dantabrom TBS-5B", for "Dantabrom TBS-4A", and for "Dantabrom TBS-5A" EPA Reg. No(s) 6836-ETU, 6836-ETE and 6836-ETG. MRID 44801904 & -05. [in-tank sanitizing data]. (PDF, 3 pp, 178K)Bruce MannEfficacy & Science Support Branch AD44801904... [More]
07/10/1997BCDMH. Review of Toxicology Data. Combined chronic/oncogenicity feeding - Rat. (83-5) MRID 44095901. (PDF, 34 pp, 2MB)Raymond LockeToxicology Branch44095901
01/29/19971-Bromo-3-chloro-5,5-dimethylhydantoin: Review of toxicology data. 18-month oncogenicity study in mice, 83-2b. MRID 44063901. Tox review 012154. (PDF, 15 pp, 892K)Raymond LockeToxicology Branch44063901
01/29/19971-Bromo-3-chloro-5,5-dimethylhydantoin (BCDMH). Addenda to Data Evaluation Records (DERs). [Addenda to Doc. No. 011997 and 011546.] MRID 44111900, 44111901, 44111902. Tox review 012153. (PDF, 3 pp, 129K)Raymond LockeToxicology Branch44111900... [More]
10/23/1996Review od Chronic (One-Year) Feeding Study in the Dog Supporting the Reregistration of 1-bromo-3-chloro-5,5- dimethylhydantoin, Case # 3055, AI 006315. (PDF, 16 pp, 970K)
 Additional Files Attachments
Kathleen DepukatAccelerated Reregistration Branch SRRD-
07/24/19961-Bromo-3-chloro-5,5-dimethylhydantoin: Review of Toxicology Data. Subchronic oral toxicity (feeding) - Dog; Range-finding study for chronic toxicity - Dog. MRID 43553101. Tox review 011997. (PDF, 12 pp, 795K)Raymond LockeToxicology Branch43553101
07/09/1996BCDMH. Review of Toxicology Data. Multigeneration Reproduction - Rat (83-4). MRID 43290601. Tox review 011975. (PDF, 26 pp, 2MB)Raymond LockeToxicology Branch43290601
05/19/1995EPA ID # 006315: 5,5-Dimethylhydantoin (DMH) - -Review of Carcinogenicity Study in Mice and Chronic Toxicity/Caarcinogenicity Study in Rats (MRID No. 433977-01 and -02). Tox review 011556. (PDF, 33 pp, 2MB)Paul ChinToxicology Branch43397701... [More]
05/12/19955,5-Dimethylhydantoin. Review of Toxicology Data. MRID 43553101. Chronic (One-Year) Toxicity (Dog). Tox review 011546. (PDF, 16 pp, 1011K)Raymond LockeToxicology Branch43553101
05/12/1995EPA ID # 006315: 5,5-Dimethylhydantoin (DMH)- Review of 90-Day Subchronic Dermal Toxicity Study in Rats (MRID No. 431739-01). Tox review 011544. (PDF, 14 pp, 712K)Paul ChinToxicology Branch43173901
02/15/1995Review of three acute estuarine toxicity tests for Halobrom (DP Barcode D171469). MRID 420761-02, -01, -03. (PDF, 4 pp, 213K)Anthony MaciorowskiEcological Effects Branch42076101... [More]
01/12/1995Review of product chemistry and toxicology studies for the chemical 1-Bromo-3-chloro-5, 5-dimethyllhydantoin. (PDF, 2 pp, 116K)Mark WilhiteAccelerated Reregistration Branch-
09/15/1994Product Chemistry Review of Halobrom (RR Case#3055, Phase 4) Page 3 removed, quality control procedures. (PDF, 3 pp, 131K)Alfred SmithRegistration Support Branch-
05/13/1994EPA ID # 006836: Registrant's Response to Agency Review of MEH (5-methyl-5-ethylhydantoin) General Metabolism Study. MRID 430204-02. Tox review 010966. (PDF, 2 pp, 131K)Paul ChinToxicology Branch43020402
09/27/1993Review of data for hydantoin submitted by Lonza Inc. Flow-through life-cycle toxicity. Daphnia magna. Early life-stage toxicity. Fathead minnow. Pages 15-22, 37-40 removed, registrant data. MRID 42721701, 42721702. (PDF, 55 pp, 2MB)Anthony MaciorowskiEcological Effects Branch42721701... [More]
03/20/1993EFED's comments on dihalodialkylhydantoins DCI (Case 3055). (PDF, 1 pp, 43K)Bernice SlutskyEnvironmental Fate & Effects Division-
08/27/1992Lonza Inc.; List C Phase IV. MRID 930760-02, -03, 04, 05, 20, 06, 27, 07, 22, 08, 09, 10. (PDF, 48 pp, 2MB)Douglas UrbanEcological Effects Branch93076002... [More]
03/30/1992ID No.: 006836-00115, Metabolism Studies with Dimethylhydantoin in Rats. MRID 42173901. Tox review 009394. (PDF, 22 pp, 1MB)Melba MorrowToxicology Branch42173901
01/07/1992ID No.: 006836-00115, 90 Day Subchronic Oral Study in Rats with Dimethylhydantoin. MRID 42009201. Tox review 008972. (PDF, 9 pp, 460K)Melba MorrowToxicology Branch42009201
05/21/1990Submission of estuarine data to support proposed label amendment for once-through use in industrial cooling water systems. Pages 13-14 removed, registrant data. MRID 409931-01, -02, -03. (PDF, 14 pp, 646K)Curtis LairdEcological Effects Branch40993101... [More]
05/21/1990Submission of estuarine data to support proposed label amendment for once-through use in industrial cooling water systems. Pages 7-8 removed, registrant data. MRID 409931-01, -02, -03. (PDF, 14 pp, 657K)Curtis LairdEcological Effects Branch40993101... [More]
01/16/1990Reg. Nos. 5785-65 and 5785-63. BromoCide Tablets, BromoCide Granules. Review Amendment Request for Additional Use Pattern and Additional Brand Name (BromoCide Tablets and Granules) (PDF, 6 pp, 1002K)
 Additional Files Attachments
Paul MastradoneChemistry Review Section-
08/23/1989Dantobrom S; EPA ID # 6836-116; Record No. 245107. MRID #s 410889-01, -02 Tox review 007447 (PDF, 3 pp, 144K)Joycelyn StewartToxicology Branch-
04/05/1989File or Reg. No. 5785-IU. Proposed registration of uses in brewery pasteurizers and recirculating cooling water systems. (PDF, 10 pp, 517K)
 Additional Files Attachments
Curtis LairdEcological Effects Branch-
06/02/1988Dantobrom S and Dantobrom P. EPA ID #s 6836-116 and 6836-118. Acc. Nos. 403313-01 and 403313-07 (PDF, 14 pp, 655K)Joycelyn StewartToxicology Branch-
05/04/1988Dantobrom S and Dantobrom P. EPA ID Nos. 6836-116; 6836-118. Acc. Nos. 403313-01 and 403313-07 Tox review 006687 (PDF, 8 pp, 542K)Joycelyn StewartToxicology Branch-
03/03/19885,5-Dimethylhydantoin and 5-ethyl, 5-methylhydantoin. EPA ID # 38906-3, -4, -7, -9, -12, -13, -14, -15. Tox Chem Nos. 366D, 568E, 309C. Product formulation information on page 1 is not included (PDF, 3 pp, 155K)Joycelyn StewartToxicology Branch-
07/17/1987File or Reg. No. 3377-EG, 3377-EE, 3377-EU. Data Review for Technical. Avian acute oral LD50, Bobwhite quail, page 5. Eight-day dietary LC50, Bobwhite, p.9; Mallard, p.12. 96-hour LC50, Bluegill, Fathead, p.15; Trout, p.18. 48-hour LC50 p.22. (PDF, 24 pp, 815K)Curtis LairdEcological Effects Branch-
07/07/1987Resubmission (Skin Irritation and Eye Irritation Data) (PDF, 4 pp, 140K)James WilsonDisinfectants Branch-
06/30/1987Dantobrom S. EPA ID No. 38906-13 and Dantobrom P, EPA ID No. 38906-15 (PDF, 19 pp, 666K)Joycelyn StewartToxicology Branch-
05/14/1987Dantobrom S, EPA ID No. 38906-13 and Dantobrom P, EPA ID No. 38906-15. Commercial/financial information on page 1 is not included Tox review 005876 (PDF, 17 pp, 891K)Joycelyn StewartToxicology Branch-
05/13/1987Reg./File No. 8959-44. Registration for use in indoor and outdoor swimming pools. Both the hydrolysis and the aqueous photodegradation studies should be repeated with a purified material... Acc. # 265455 and 265456. (PDF, 4 pp, 193K)Akiva AbramovitchExposure Assessment Branch-
05/12/1987Registration for Use in Indoor and Outdoor Swimming Pools and Spas (PDF, 4 pp, 206K)Akiva AbramovitchExposure Assessment Branch-
05/01/1987Reg./File No. 3377-EG, 3377-EE, 3377-EU. Registration for use in swimming pools. (PDF, 8 pp, 356K)Akiva AbramovitchExposure Assessment Branch-
02/17/19878622-EL Registration for use in indoor and outdoor swimming pools and spas Hydrolysis and Photodegradation in Water. Acc. 264468 (PDF, 4 pp, 231K)James AdamsExposure Assessment Branch-
01/12/1987Bromochloro-5,5,dimethylhydantoin; 1-bromo- 3-chloro-5,5-dimethylhydantoin EPA ID# 8622-EL Mutagenicity. Acc. 264468. Tox review 005654 (PDF, 10 pp, 585K)Joycelyn StewartToxicology Branch-
11/26/1986Resubmission - Tox Data (PDF, 3 pp, 150K)James WilsonDisinfectants Branch-
10/31/1985Dantobrom, EPA Registration No. 38906-14. Dantobrom P, EPA File Symbol 38906-RL. Data Requirements for Use in Spas and Swimming Pools. Manufacturing process information on page 2 is not included (PDF, 4 pp, 296K)Joycelyn StewartToxicology Branch-
07/15/19858622-EL New Application Acute Oral, Acute Dermal, Skin Irritation, Eye Irritation Acc. 258165 (PDF, 3 pp, 125K)James WilsonDisinfectants Branch-
07/11/19858622-EL Submission of data to support proposed microbicide uses Acc. 258164 (PDF, 2 pp, 84K)Leslie TouartEcological Effects Branch-
03/12/1985Dantobrom, Dantobrom S, & Dantobrom P Data Requirements for Use in Spas and Swimming Pools - Glycol (PDF, 2 pp, 76K)Robert ZendzianToxicology Branch-
02/26/1985Review Protocols (Hydrolysis Study) (PDF, 3 pp, 120K)Samuel CreegerExposure Assessment Branch-
11/13/1984Reg./File No. 8959-UN. Request for waiver from the aqueous photolysis study. (PDF, 3 pp, 129K)Samuel CreegerExposure Assessment Branch-
11/06/1984File No. 8959-UU. Brominating Compounds. Proposed Registration of Uses in Spas and Hot Tubs (PDF, 24 pp, 879K)Curtis LairdEcological Effects Branch-
09/27/1984Response to Data Requirements (PDF, 4 pp, 176K)Samuel CreegerExposure Assessment Branch-
09/12/1984New Product Registration (PDF, 3 pp, 101K)William CampbellDisinfectants Branch-
09/12/1984Reg./File No. 38906-RL use in swimming pools. Discussion of Data. The three active ingredients in the product were... previously reviewed (13 April 1984). Page 6 removed, confidential statement of formula. (PDF, 10 pp, 645K)Samuel CreegerExposure Assessment Branch-
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